Genetic Diabetes Nurse

The Genetic Diabetes Nurse: A new service in Wales


Monogenic abnormalities cause 1-2% of all diagnosed cases of diabetes. Conditions such as Neonatal Diabetes, Maturity Onset Diabetes of the Young (MODY) and Renal Cysts and Diabetes are examples. Recognition of these conditions is however not always straightforward and >90% of cases are initially misdiagnosed as having either Type 1 or Type 2 diabetes. If a case is confirmed (by molecular genetic testing) it can prevent the use of inappropriate therapies such that both diabetes control and quality of life can be optimised. Following diagnosis there are implications for other family members in terms of both increased vigilance and pharmacological treatment options.


The Royal Devon and Exeter NHS Foundation Trust is the UK referral centre for genetic testing in monogenic diabetes and has developed a UK-wide network of specialist nurses whose remit is to provide local sources of education as well as facilitating the diagnosis and management of cases of monogenic diabetes. This service began in 2002 but there has not previously been a post in Wales which has one of the lowest rates of identified cases of monogenic diabetes in the UK.

Features of monogenic diabetes

1. Maturity onset diabetes of the young (MODY) 
Diagnosis before the age of 25 years
Diabetes passed down from an affected parent to their child
May be managed with diet or sulphonylurea

2. Neonatal diabetes
Diagnosis <6 months of age
Often no family history

3. Renal cysts and diabetes (RCAD)
Renal developmental abnormalities (most often cysts) and diabetes
In 40% of cases neither parent is affected

Role of the Genetic Diabetes Nurse

  • Raise awareness within our region
  • Identifying families fitting diagnostic criteria
  • Facilitate referral for genetic testing and supporting individuals with positive result through treatment change if appropriate
  • Following up other family members and liaising with their local health care practitioners

The Monogenic Diabetes Nurse

There is currently one Genetic Diabetes Nurse who is covering Wales (contact details below). This individual is funded by the UK referral centre based in Exeter and has one day per week to dedicate to this issue.

Further Information

More information about monogenic diabetes and genetic testing is available at

Genetic Diabetes Nurse: Gaynor Harrison

Royal Glamorgan Hospital

Lead Consultant for Wales: Sam Rice
Diabetes Centre 
Prince Philip Hospital
SA14 8QF

New Genetic Diabetes Referral Information Document 2013

Information of Maternally inherited diabetes and deafness (MIDD)